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(also termed “scFv”). From this antibody library, drug candidates directed to any target molecule can be developed. The design of the library enables the development of highly functional antibodies.
The individual antibody fragments in
have distinct specific sequences in the six so-called hypervariable regions which constitute the antibody surface that binds to the target molecules. The rest of the scFv sequence is identical in all antibodies in the library and was selected to achieve optimal properties in regard to e.g. stability and manufacturability. The variability in ..
is designed to mimic and exceed the variability in natural human antibodies.
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