Main > A1. CORP. INDEX. Un-Uz > University Tokyo/P C2 > 2005. 10.10.2005. (Mice Pheromone)

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Mouse pheromone found in tears
Pheromones—compounds that serve as a means of chemical communication between animals of the same species—are usually, though not always, volatile compounds. Biologist Kazushige Touhara and coworkers at the University of Tokyo have discovered a new nonvolatile sex-specific pheromone secreted from the tear glands of male mice (Nature 2005, 437, 898). The 7-kilodalton peptide, which the researchers call exocrine gland-secreting peptide-1, is secreted from the eyes of male mice and transferred to females through direct contact. The peptide stimulates neurons in the females that are usually associated with pheromone response. The pheromone does not elicit a response in male mice. Through genetic analysis, the researchers found that the gene encoding the peptide is part of a previously unrecognized gene family.




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