Main > MICROCHEMISTRY > Applications > Pharma.>Glycosides>NonCryogenic Pro > Co.: USA. B (Patents) > Description
It includes lithiating an aromatic reactant having a leaving group in a microreactor to form a lithiated anion species. This anion species is then coupled with a carbonyl-substituted reactant to form a glycoside. The lithiating and coupling steps are rapid and highly exothermic. The approach, according to the patent claims, offers reduced by-products, improved yields, and decreased costs of manufacture.
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