Main > NEUROLOGY. > Alzheimer's Disease > Beta Secretase [BACE1 (Abbrev.)] > Aspartyl Protease 2 (Asp2). > Inhibitor. > Identification Method. > Patent. > Claims Etc > Claim 1: Purified Protein AA Seq.: > FIG. 2 (SEQ ID NO: 6). Claim 2: > Production Process: Culturing Host > Cell Transformed with Nucleic Acid > Encoding Polypeptide; Expresses > Polypeptide; Contiguous AA Seq. > FIG. 2 (SEQ ID NO: 6) & Isolating > Expressed Polypeptide. Claim 3: > Purified Polypeptide AA Seq. > 95% > Identical to Fragment of Asp2 > Aspartyl Protease Protein AA Seq. > SEQ ID NO: 6, Wherein Fragment > is Contiguous Fragment Includes > Aspartyl Protease Active Site > Tripeptides DTG & DSG & Exhibits > Aspartyl Protease Activity Involved > Processing APP into Amyloid Beta; > Lacks a Transmembrane Domain;
Lacks a Transmembrane Domain;'s subsections
Claim 4: Heterologous Peptide Tag.
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