Main > NEUROLOGY. > Alzheimer's Disease > Beta Secretase [BACE1 (Abbrev.)] > Aspartyl Protease 2 (Asp2). > Inhibitor. > Identification Method. > Patent. > Claims Etc > Claim 1: Purified Protein AA Seq.: > SEQ ID NO: 73 Aspartyl Protease > Activity toward APP. Claim 2: > Protein Lacks Transmembrane Domain > Claims 3,4: Includes Heterologous > Peptide Tag. Claims 5,6: Protein > Production Method. Culturing > Host Cell Transformed with Nucleic > Acid EnCoding SEQ ID NO: 73 Protein > & Isolating Expressed Protein. > Claim 7: Asp2 Inhibitor Identifying > Method: a) Measure Proteolytic > Activity of Asp2 in Pres. & Absence > of Test Ag.; b) Decreased Activity > in pres. of Ag. Identifies Ag. as > Inhibitor. Claim 8: Cl. 7a Proteoly
Inhibitor. Claim 8: Cl. 7a Proteoly's subsections
tic Activity of Asp2 Measured
Inhibitor. Claim 8: Cl. 7a Proteoly's products
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