Main > PNEUMOLOGY > Cystic Fibrosis > Treatment > Adenoviral Therapy > CFTR Gene

Product France. USA. TU

PATENT ASSIGNEE'S COUNTRY France; USA
UPDATE 01.00
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS Method of expressing a DNA segment encoding the CFTR protein in the lung of a mammal, comprising
- Directly adm to lung of mammal a replication deficient ade
noviral construct comprising a DNA segment encoding the
CFTR protein operably linked to a promoter
Wherein said adenoviral construct comprises a deletion in the E1a, E1b & E3 regions of the adenoviral genome, under conditions such that said DNA segment is expressed & a sufficient quantity of said protein is thereby produced to increase Cl anion secretion in lung
PATENT PHOTOCOPY Available on request

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