PATENT ASSIGNEE'S COUNTRY | France; USA |
UPDATE | 01.00 |
PATENT ASSIGNEE | This data is not available for free |
PATENT CLAIMS |
Method of expressing a DNA segment encoding the CFTR protein in the lung of a mammal, comprising - Directly adm to lung of mammal a replication deficient ade noviral construct comprising a DNA segment encoding the CFTR protein operably linked to a promoter Wherein said adenoviral construct comprises a deletion in the E1a, E1b & E3 regions of the adenoviral genome, under conditions such that said DNA segment is expressed & a sufficient quantity of said protein is thereby produced to increase Cl anion secretion in lung |
PATENT PHOTOCOPY | Available on request |
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