Main > NEUROLOGY. > Kainic Acid > Use: Research Tool > Algae (Digenea simplex)-Derived

Product UK. T

CLASSIFICATION Market
MANUFACTURING Derivable from "Digenea simplex" alga seaweed. Algae grows in militarily sensitive area between Taiwan & the Philippines. Area is under Taiwanese control.
Kainic acid is then extracted from the algae. Obtention of kainic acid has not been as straightforward as COMPANY had hoped. So far, the COMPANY has extracted only 500 mg from the seaweed, a fifth of what it expected. Worse, the prodt is only 96% pure - researchers require 99% purity
MARKETER'S COUNTRY UK
PRODUCER'S COUNTRY UK
SALES VALUE Kainic acid sells to labs for US$ 100 per 10 mg. World demand estimated in US$ 150,000 per year
THERAPEUTIC CLASS Anthelmintic (Nematodes)
UPDATE 03.00
USES It is a research tool with no possibility of becoming a clinical drug for neurological use. In brains, at low doses, it causes stimulation of brain cells. But at higher concn., it causes seizures [in live animals] & subsequently causes widespread destruction of neuronal tissue. Although it is fine for killing worms in the gut, it clearly has no ability to pass the blood-brain barrier. If you can simulate this brain degeneration in the lab, then you can try to find compds that can prevent it. The coined expression is excitotoxicity, & one of the reasons why this research goes on is because this is pretty much what happens after a stroke - glutamic acid is then the agent, kainate mimics one subset of glutamate effects. It is because its pharmacological action makes it so toxic in the brain that it is so interesting
COMPANY This data is not available for free
CONTACT This data is not available for free
MARKETING BY This data is not available for free
PRODUCTION BY This data is not available for free
SUPPLIER The COMPANY has found a Co in Taipei that has agreed to supply "Digenea simplex" imported from Japan

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