PATENT ASSIGNEE'S COUNTRY | Denmark |
UPDATE | 09.99 |
PATENT ASSIGNEE | This data is not available for free |
PATENT CLAIMS |
Protein which is - Protein which is purified, & which is released from metaboli zing mycobacteria belonging to the tuberculosis complex & can be isolated from filtrates from such mycobacteria grown as shaken cultures for 7 days, & has MW 3-16 kDa as de termined by SDS-PAGE & Ag staining Which protein induces a release of IFN-gamma of > 1500 pg/ml from reactivated memory T-lymphocytes withdrawn from a C57B1/6j mouse within 4 days after the mouse has been rechallenge infected with said mycobacteria, the induction performed by the addition of said protein to a suspension comprising 200,000 reactivated memory T-cells per ml, the addition of protein resulting in a concn of 1 micro.g per ml of suspension, the release of IFN-gamma being assessable by determn of IFN-gamma in supernatant harvested 2 days after the addition of the protein to suspension Said protein having the ability of eliciting a delayed type hypersensitivity reaction |
PATENT PHOTOCOPY | Available on request |
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