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RESEARCH Taking advantage of the fact that membranes can be designed to recognize, isolate, and transport a desired molecule out of a mixture, researchers at the University of Florida, Gainesville, have carried out chiral separations using an antibody-based nanotube membrane.



Chemistry professor Charles R. Martin and coworkers Sang Bok Lee, David T. Mitchell, and Lacramioara Trofin prepare the antibody-based membranes from alumina films that have cylindrical pores with nanoscopic diameters. They grow silica nanotubes within the pores by sol-gel chemistry. Then they install aldehyde silanes in the inner surfaces of the tubes. Finally, the researchers attach antibody fragments by reacting the aldehyde groups with the free amino sites of the protein.

Using membranes prepared in this way, they successfully separated enantiomers of finro

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