COMMENTS | Sialic acid (N-acetylneuraminic acid) groups are found at the ends of many glycans, glycoproteins, and glycolipids, where they play important roles in cellular and molecular recognition and communications. Hence, the structure of the enzyme that transfers these groups to biomolecular acceptors "has long been one of the major goals of structural and mechanistic glycobiology," comments Gideon J. Davies of the University of York, in England |
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