PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 06.99 |
PATENT ASSIGNEE | Alkermes Controlled Therapeutics (Cambridge; Mass.) |
PATENT CLAIMS |
Method of prepg biodegradable, biocompatible polymer microparticles (a) Prepg first phase comprising drug, polymer & solvent (b) Prepg second phase immiscible with (a) (c) Mixing (a) & (b) to form emulsion in which (a) is disperse phase (d) Immersing emulsion in a quench liquid that comprises quench medium & quantity of said solvent, wherein quantity of said solvent is selected to control rate of extraction of solvent from disperse phase (e) Isolating disperse phase in form of microparticles Solvent: EtOH |
PATENT PHOTOCOPY | Available on request |
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