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Product Polymer. Microparticle. Prepn. USA. A.

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 06.99
PATENT ASSIGNEE Alkermes Controlled Therapeutics (Cambridge; Mass.)
PATENT CLAIMS Method of prepg biodegradable, biocompatible polymer microparticles
(a) Prepg first phase comprising drug, polymer & solvent
(b) Prepg second phase immiscible with (a)
(c) Mixing (a) & (b) to form emulsion in which (a) is disperse
phase
(d) Immersing emulsion in a quench liquid that comprises
quench medium & quantity of said solvent, wherein quantity
of said solvent is selected to control rate of extraction of
solvent from disperse phase
(e) Isolating disperse phase in form of microparticles
Solvent: EtOH
PATENT PHOTOCOPY Available on request

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