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There is increasing interest in using stem cells as a drug discovery tool, for example as an aid in identifying small molecules or proteins which are able to mature a brain stem cell into a differentiated cell such as a neuron. Similarly, it has been suggested that regional stem cells may be a sensitive indicator of organ toxicity, and that panels of stem cells may be used to screen potential lead compounds for toxicity. Co. has a large collection of human and murine cell lines and cell populations. The best-characterised of these human cell lines are now being offered to pharmaceutical companies and academic institutions for use as a drug discovery or research tool, under the product name (See trademark). These cells grow rapidly in serum-free conditions, have been adapted for use in high through-put formats, and differentiate rapidly in vitro to yield a high neuronal content
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