DEVELOPMENT |
Advanced BioAnalytical Services, Inc. (ABS) has signed an agreement with PE Biosystems Group to jointly pursue the development of a combined liquid chromatography and mass spectrometry (LC/MS) interface in a single miniaturized device. The LC/MS device would combine the power of ABS's electrospray ionization (ESI) nozzle technology with PE Biosystem's novel miniaturized separation systems, facilitating higher sample throughputs, and smaller sample sizes at lower cost. Miniaturized ESI mass spectrometry would provide improved selectivity and information content over spectrophotometric detection-based technologies. The LC/MS device developed under this collaboration would initially be designed to interface with PE Biosystems' Mariner ESI/time-of-flight mass spectrometer. The collaborators envision the LC/MS device to have substantial benefits for use with all PE Biosystems' LC/MS platforms particularly for use in drug discovery markets including pharmacogenomics and proteomics. "We are extremely excited about this new collaboration with PE Biosystems," said Dr. Jack Henion, co-founder, President and CEO of ABS. "We believe the LC/MS device will provide a tremendous improvement in high-throughput mass spectral analyses for the determination of pharmaceutically important compounds in a faster, better, and cheaper format. We are very pleased about the opportunity to collaborate with PE Biosystems which is an acknowledged leader in the life sciences industry," said Henion. "ABS's innovation in electrospray ionization technology, combined with PE Biosystems' separation technology, makes for a new way to treat a sample prior to mass spectrometry analysis," said Joseph Malandrakis, Vice President and General Manager of PerSeptive Biosystems, a division of PE Biosystems. "This collaboration represents feasibility work and is part of PE Biosystems' effort to identify technologies that complement its existing research. We are happy to be working with ABS." |
UPDATE | 08.05.2000 |
ALLIANCE |
- Advanced BioAnalytical Services - PE Biosystems |
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