| CLINICAL STUDY |
MICE's NEUROPROTECTION STUDIES: - In mice that received MPTP, brain dopamine levels in the area of the brain affected by Parkinson's fell to 40% of nor mal - If mice were pretreated with the naphthoquinone deriv, their dopamine levels remained > 60% of normal |
| MECHANISM OF ACTION |
- Naphthoquinone deriv isolated from tobacco leaves; that slows the breakdown of dopamine, a neurotransmitter that's depleted in brain of patients with Parkinson's disease. - Naphthoquinone deriv was also found to inhibit Monoamine oxidase |
| SYNTHESIS | See LITERATURE REF. |
| UPDATE | 04.00 |
| AUTHOR | This data is not available for free |
| LITERATURE REF. | This data is not available for free |
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