| STUDY |
Author says his work on calcium phosphate bone cements is an example of how chemistry can be applied to the development of medical and dental materials. Several calcium phosphate cements set to form HAP crystals, which are similar to those found in teeth and bone. When placed in a bone defect, the crystals are gradually replaced by bone and, with time, the defect is healed without a trace of the cement left in bone. The first calcium phosphate cement (CPC) was discovered at PRC in the 1980s and later approved by the Food & Drug Administration for reconstruction of the frontal sinus and augmentation of craniofacial skeletal defects. The low strength and brittle nature of many CPCs limit their use to nonload-bearing applications, author says. However, ongoing research at PRC aims to improve strength and bony ingrowth in CPCs through the introduction of synthetic bioresorbable fibers. "The incorporation of such fibers can significantly improve the strength and fracture resistance of materials," author says, to the point that enhanced CPCs might one day be used for stress-bearing locations in the body--such as molar teeth, for example--or for reconstructive treatments for thin bones |
| UPDATE | 06.03 |
| AUTHOR | This data is not available for free |
| LITERATURE REF. | This data is not available for free |
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