Main > ORGANIC CHEMICALS > Reduction Agents > Reagent. > Sodium Aluminum Hydride (SAH). > Production

Product USA. A

CLASSIFICATION Market
ECONOMY Sodium aluminum hydride (SAH) is now available from Co. as a cost-effective alternative to lithium aluminum hydride (LAH). Use of LAH in large-scale reductions is inhibited by the reagent's high cost. At present, SAH is up to 20% less expensive than LAH.
OBSERVATION'S SAH has the same reactivity profile as LAH, but in some cases it is less reactive but more selective. For example, cinnamaldehyde reduction with LAH proceeds completely to hydrocinnamyl alcohol, whereas the reaction with SAH proceeds partially--to cinnamyl alcohol--or fully, depending on the stoichiometry. Furthermore, when the reactivity of SAH is lower than that of LAH at low-temperature conditions, usually a modest increase in temperature gives suitable results. "In such cases, the combination of a lower cost reagent and lower cooling costs can bring significant cost advantages
UPDATE 02.03
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