PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 06.99 |
PATENT ASSIGNEE | This data is not available for free |
PATENT CLAIMS |
Method of screening test compds for ability to decrease nNOS activity - Contacting test compd with mixt of Protein Inhibitor of NO (PIN-1) protein shown in SEQ ID NO:2 & first & second pro teins comprising nNOS dimerization domain, wherein said domains confer upon first & second proteins the ability to bind to each other in the absence of PIN-1 & in absence of test compd - Measuring the amount of PIN-1 that is bound to first or se cond protein, wherein a decrease in amount of first & se cond protein bound to each other is indicative of ability of test compd to decrease nNOS activity |
PATENT PHOTOCOPY | Available on request |
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