COMMENTS | The structure "confirms the broad picture of calcineurin inhibition" provided by earlier structure studies. For example, it once again highlights the plasticity of the calcineurin binding site, he says. However, the ability to design improved immunosuppressants will also depend on future studies on ways to reverse the nephrotoxicity and other serious side effects triggered by immunosuppressant-induced calcineurin inhibition |
UPDATE | 09.02 |
AUTHOR | This data is not available for free |
LITERATURE REF. | This data is not available for free |
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