DESCRIPTION |
Fluorous mixture synthesis makes it possible to run reactions on a number of fluorous-tagged starting materials and then easily separate and identify the reaction products.
First, fluorous tags of different chain lengths are added to a series of starting materials. The tagged substrates are mixed and taken through a multistep reaction sequence. Fluorous chromatography is then used to separate the tagged product mixtures, based on the fluorine content of the different tags. Finally, compounds in the separate solutions are "detagged" to release the final products
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