| TECHNOLOGY |
A new generation of phase-trafficking techniques was introduced in the 1990s, when authors developed polymer-supported scavenging techniques that can be used combinatorially. With these techniques, you carry out a reaction in solution and afterward use polymer-supported affinity agents to scavenge reagents and by-products out of solution. Filtering the solution to remove the scavenger leaves the product in solution phase. In many cases, this method eliminates the need to purify products chromatographically.
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