| OBSERVATION'S |
The dispute over whole-genome shotgun versus clone-by-clone sequencing is still going on today. A few months ago, CONTACT and two other leaders of the international HGP published a paper concluding that the `C` Co. team had relied to such a great extent on public HGP mapping and sequencing data that whole-genome shotgun sequencing had not actually generated an independent sequence of the human genome. They claimed that `C` had essentially used the public mapping data to organize its private shotgun data and thus hadn't demonstrated that whole-genome shotgun sequencing alone can produce a finished mammalian sequence. `C` published a formal rebuttal.
|