| SYNTHESIS | developed a new synthesis for its proprietary Cl-MeO-BIPHEP ligands [(5,5'-dichloro-6,6'-dimethoxybiphenyl-2,2'-diyl)-bis(diphenylphosphine)s]. These ligands deliver greater than 98.7% enantioselectivity in asymmetric hydrogenations of carbonyl groups and carbon-carbon double bonds. The method enables a wide spectrum of alkyl groups to be introduced, allowing "us to fine-tune the catalyst beyond what was possible before |
| UPDATE | 06.02 |
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