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Nurse, using a different yeast strain, also identified many of the genes that regulate the cell cycle. In particular, he identified the gene that controls passage into the part of the cell cycle known as mitosis, when chromosomes separate. He later showed that his gene and Hartwell's were the same, establishing that this gene's product regulates different phases of the cell cycle. Nurse also found the corresponding gene in humans. The gene encodes a protein that in humans is called cyclin-dependent kinase 1 (CDK-1).
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