| SUBJECT | Hunt, studying sea urchins, identified a protein he named cyclin because its level rises and falls during the cell cycle. Cyclins, it is now known, bind to CDKs to activate them. The amount of CDK molecules remains constant in a cell, but the molecules' activity varies because of the regulatory function of the cyclins. |
| UPDATE | 10.01 |
| AUTHOR | Nurse is director-general of Britain's Imperial Cancer Research Fund, London, where Hunt is a principal scientist. |
| LITERATURE REF. | This data is not available for free |
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