| OBSERVATION'S |
However, many process chemists advise against thinking that the synthesis developed during drug discovery must be practical. "The most important thing about the discovery route is that it is able to generate a lot of structural diversity," says author. "The discovery chemist is looking to make as many different types of analogs as possible. A diverse synthesis where they're making a lot of intermediates allows them the luxury of making many compounds that can be tested. Discovering new drugs is the goal, and coming up with the perfect process from day one is an unnecessary burden for the medicinal chemist."
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