| STRUCTURE | (Resin)-C6H4-CH2-O-(CH2)3-N=C=N-C6H11 (Reagent) |
| OBSERVATION'S | If necessary 1-hydroxybenzotriazole (HOBt) is added to reaction to suppress a rearrangement to an unreactive acylurea. HOBt converts the reactive intermediate to the HOBt active ester, which then reacts with the amine to generate the amide. The HOBt is released & is readily scavenged with MP-Carbonate or PS-Trisamine |
| SYNTHESIS |
Reagent+RCO2H=[R-CO2-C(-NH-)=N-C6H11]+R'NH2= R-CONHR'+(Resin)-NH-CO-NH-C6H11 |
| UPDATE | 05.02 |
| COMPANY | This data is not available for free |
| LITERATURE REF. | This data is not available for free |
| PHONE NUMBER | This data is not available for free |
| WEBSITE | This data is not available for free |
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