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Product Methioninase. Production. USA. A.

PATENT ASSIGNEE'S COUNTRY USA.
UPDATE 04.99
PATENT ASSIGNEE AntiCancer (San Diego; Ca)
PATENT CLAIMS Host cell transformed with an expression module for the mfg of methioninase, said module comprising a nucleotide sequence encoding methioninase operably linked to a T7 RNA polymerase promoter, wherein
- Said sequence encodes a protein having aminoacid se
quence SEQ ID NO:2
- Said expression module is stable in host cell & directs con
stitutive expression of said methioninase encoding sequen
ce in host cell
- Wherein said methionine is produced at level 5 - 75 % of
the total protein of host cell
PATENT PHOTOCOPY Available on request

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