Main > MEDICINE > Medical Polymers > Poly(Urethane) (PU) > Caprolactone/Dioxanone Olig Diol PU > Memory-Shape. BioDegradable PU > Development. by

Product DE. M

TECHNOLOGY When heated, SHAPE-MEMORY POLYMERS transform from a temporary initial shape into a often drastically different permanent shape. This shape-
shifting ability has many potential applications in MEDICINE if biocompa
tible or biodegradable materials can be developed.
Now, authors report the first BIODEGRADABLE, thermoplastic shape-
memory polymers & show that they can be processed from melt or soln.

The linear multiblock copolymers [Poly(Urethane)] are prepd by coupling:

Oligo(Epsilon-Caprolactone)Diol + Oligo(p-Dioxanone)Diol with
Alkyl DiIsocyanate

The polymer can be deformed up to 400% between the temporary & permanent shapes
UPDATE 04.02
USES As a example application, the polymer was extruded into a FILAMENT that was elongated & used to loosely SUTURE a INCISION on a rat. Upon heating, the suture contracted to its permanent shape to snugly close the incision. The polymers could someday be used to make medical devices that are IMPLANTED LAPAROSCOPICALLY & then thermally expanded into a permanent shape.
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