| SYNTHESIS |
(R)-1-Amino-1-(3,4-methylenedioxyphenyl)butane. Chemists begin by forming the Schiff base of D-phenylglycinnamide with piperonal. Reaction of the Schiff base with allylzinc bromide adds 3 C across the imine to give a amino butene in 88% yield & > 99% ee. Hydrogenation cleaves the phenylglycine auxiliary, leaving the free amine |
| UPDATE | 12.01 |
| COMPANY | This data is not available for free |
| CONTACT | This data is not available for free |
| LITERATURE REF. | This data is not available for free |
|
Want more information ? Interested in the hidden information ? Click here and do your request. |