| STRUCTURE |
This protein disrupts a signaling pathway involved in the release of defensive proteins Lethal factor exerts its effect by recognizing a signaling molecule, the kinase MAPKK-2. This molecule uses a tail at its N-terminus to dock onto another kinase in the signaling pathway. Lethal factor clips to this tail, cutting communication between the 2 kinases. Crystal structure shows how lethal factor recognizes & cleaves the target peptide |
| UPDATE | 10.01 |
| AUTHOR | This data is not available for free |
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