| TECHNOLOGY |
Protein crystals have very large solvent-filled channels into which you can diffuse lots of things. Technique involves diffusing into those channels organic solvents that ressemble the functional groups of drugs & other ligands & then determi ning if & where they bind. For example “if you’re interested in where peptides bind, all you’ve got to do is soak your crystal in dimethylforma mide & it will tell you. If you want to know where aromatic rings bind, soak in benzene |
| UPDATE | 11.01 |
| AUTHOR | This data is not available for free |
| LITERATURE REF. | This data is not available for free |
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