Main > PHARMA. > Druglike Molecule Judgement > System of Criteria Development

Product USA. B

DEVELOPMENT Has devised a system of criteria for what a molecule "look like" in order to be judged druglike.
System awards pharmacophore points based on combinations of sulfonyl, amino, hydroxyl, & keto groups. Also, molecules must have at least one ring but no more than one -COOH to be judged druglike
UPDATE 09.01
ADDRESS Bayer Research Center, West Haven, Conn
AUTHOR Muegge Ingo
LITERATURE REF. J. Med. Chem., 44, p. 1841 (2001)

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