DEVELOPMENT |
Has devised a system of criteria for what a molecule "look like" in order to be judged druglike. System awards pharmacophore points based on combinations of sulfonyl, amino, hydroxyl, & keto groups. Also, molecules must have at least one ring but no more than one -COOH to be judged druglike |
UPDATE | 09.01 |
ADDRESS | Bayer Research Center, West Haven, Conn |
AUTHOR | Muegge Ingo |
LITERATURE REF. | J. Med. Chem., 44, p. 1841 (2001) |
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