Main > ORGANIC CHEMICALS > Aliphatics > Acids > Hydroxy. Alpha > Amino. Beta

Product DE. D.

CORP. SALE Ph-CH(NH-Me)-CHOH-COOH
PATENT ASSIGNEE'S COUNTRY Germany
UPDATE 08.99
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS - Reducing (S) or (R) Phenyl glycine with Hydride reagent
- Reacting (S) or (R)-Ph glycinol [Ph-CH(NH2)-CH2OH] with
Me amine protecting agent to provide an N-protected beta-
amino alc. (S)- or (R)-N-(H,Me) Ph glycinol of formula:
Ph-CH(NHMe)-CH2OH (I)
- (I) is oxidized to give (S)- or (R)-N-(H,Me)-Ph glycinal of
formula: Ph-CH(NHMe)-CHO (II)
- (II) reacted with CN ions to yield
Ph-CH(NHMe)-CHOH-CN (III)
- (III) hydrolyzed with HCl to yield title mixt.
- Isolation
PATENT PHOTOCOPY Available on request

Want more information ?
Interested in the hidden information ?
Click here and do your request.


back