CORP. SALE | Ph-CH(NH-Me)-CHOH-COOH |
PATENT ASSIGNEE'S COUNTRY | Germany |
UPDATE | 08.99 |
PATENT ASSIGNEE | This data is not available for free |
PATENT CLAIMS |
- Reducing (S) or (R) Phenyl glycine with Hydride reagent - Reacting (S) or (R)-Ph glycinol [Ph-CH(NH2)-CH2OH] with Me amine protecting agent to provide an N-protected beta- amino alc. (S)- or (R)-N-(H,Me) Ph glycinol of formula: Ph-CH(NHMe)-CH2OH (I) - (I) is oxidized to give (S)- or (R)-N-(H,Me)-Ph glycinal of formula: Ph-CH(NHMe)-CHO (II) - (II) reacted with CN ions to yield Ph-CH(NHMe)-CHOH-CN (III) - (III) hydrolyzed with HCl to yield title mixt. - Isolation |
PATENT PHOTOCOPY | Available on request |
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