SYNTHESIS | Researchers make it in 7 steps & 20% overall yield. The key step is closing the pyrrolidone ring by an asymmetric ene reaction of an amide of those starting compds. They polish the prodt to 100% enantiomeric excess by crystallization of the (+)-ephedrine salt |
UPDATE | 01.01 |
USES | in research on epilepsy & Alzheimer's disease |
AUTHOR | This data is not available for free |
LITERATURE REF. | This data is not available for free |
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