Main > PHARMA. > Enzyme Inhibitors > Helicase > Inhibitor > Quantitative Solid Phase Assay

Product USA. B

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 09.99
PATENT ASSIGNEE Boehringer Ingelheim Pharmaceuticals Inc
PATENT CLAIMS (a) Immobilizing on solid support under acid pH conditions a helicase substrate comprising single stranded nucleic acid polymer hybridized to a labeled helicase reaction prodt., wherein the said prodt is detectable in soln by helicase activity
(b) Contacting immobilized helicase substrate with test substance to produce reaction premix
(c) Contacting under neutral or slightly alkaline pH conditions the said premix with helicase capable of releasing labeled helicase reaction prodt into soln by helicase activity
(d) Measuring the amount of labeled helicase reaction prodt released into soln as function of time
PATENT PHOTOCOPY Available on request

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