TECHNOLOGY |
Scientists in the Co. chemical dev. dept. report a specific nucleophilic p-hydroxylation of 1-nitro naphthalene that is amenable to scale-up. Their results may make nucleophilic substitutions attractive for aromatic fine chemicals production Scientists find that treatment of 1-nitronaphtha lene with cumyl hydroperoxide & KOH in 75% aq dimethyl sulfoxide yields 82% of 4-nitro-1-naph thol & none of the 1-nitro-2-naphthol that is so hard to separate from it. 1,5-Dinitronaphthalene yields 83% of 4,8-dinitro-1-naphthol & no 1,5-di nitro-2-naphthol |
UPDATE | 04.00 |
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