PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 03.00 |
PATENT ASSIGNEE | This data is not available for free |
PATENT CLAIMS |
Production method by (a) co-transferring cells permissive for AAV replication with (i) A recombinant vector engineered to express decreased levels of adeno-associated REP 76/68 protein with respect to levels of expression observed when the host cells express adeno-associated REP 76/68 under regulatory control of its native promoter (ii) A recombinant vector engineered to express increased levels of adeno-associated REP 40/52 & CAP protein with respect to levels of expression observed when the host cells express adeno-associa ted REP 40/52 & CAP under regulatory control of their native promoter (iii) A recombinant AAV vector which contains a foreign DNA seq. & which can be incorporated into an infectious AAV virion & (b) collecting the virions produced |
PATENT PHOTOCOPY | Available on request |
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