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Product USA. C

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 03.00
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS Production method by (a) co-transferring cells permissive for AAV replication with
(i) A recombinant vector engineered to express decreased levels of adeno-associated REP 76/68 protein with respect to levels of expression observed when the host cells express adeno-associated REP 76/68 under regulatory control of its native promoter
(ii) A recombinant vector engineered to express increased levels of adeno-associated REP 40/52 & CAP protein with respect to levels of expression observed when the host cells express adeno-associa
ted REP 40/52 & CAP under regulatory control of their native promoter
(iii) A recombinant AAV vector which contains a foreign DNA seq. & which can be incorporated into an infectious AAV virion & (b) collecting the virions produced
PATENT PHOTOCOPY Available on request

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