PATENT ASSIGNEE'S COUNTRY | Germany |
UPDATE | 02.00 |
PATENT ASSIGNEE | ASTA Medica |
PATENT CLAIMS |
14-18C alkylphosphocholine prepn - Reacting 14-18C n-alkanol with P oxychloride in presence of halogenated hydrocarbon in single vessel - Reacting prodt without isolation in halogenated hydrocar bon with choline salt in presence of basic substance to form phosphoric acid diester chloride - Hydrolyzing phosphoric acid diester chloride to liberate alkylphosphocholine crude prodt in organic phase - Washing the organic phase at least one time with a solvent comprising mixt selected from water & acid substance - Separating the organic phase & evaporating the solvent to obtain alkylphosphocholine crude prodt - Suspending said crude prodt in saturated aliphatic ketone woth > 3 C atoms - Recovering the alkylphosphocholine |
PATENT PHOTOCOPY | Available on request |
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