| PATENT ASSIGNEE'S COUNTRY | Japan |
| UPDATE | 12.99 |
| PATENT ASSIGNEE | This data is not available for free |
| PATENT CLAIMS |
- Blood collection means for collecting blood from a patient suffering from an inflammatory disease - Anticoagulant mixing means for mixing an anticoagulant into the collected blood, said anticoagulant having the ability to suppress an increase in concn of at least one pla telet factor in the collected blood, said at least one platelet factor being selected from: Beta-thromboglobulin & platelet factor 4 - Blood transportation means for transporting the anticoagu lant-contg blood at flow rate 20-200 ml/min - Blood treating means having a blood inlet & blood outlet & contg platelet activating means having the ability to increa se, upon treat. of blood with said blood treating means, the concn of said at least one platelet factor in the blood, & - Blood returning means for returning the treated blood to said patient - Said blood collection means, said anticoagulant mixing means, said blood transport means, said blood treating means & said blood returning means being liquid-tightly connected in this order through a tubing Wherein, when extracorporeal blood circulation is conducted using said system with respect to blood from said patient, said system is capable of providing treated blood satisfying at least one requirement selected from (1) & (2) - (1) Having a beta-thromboglobulin concn in range 1,000- 20,000 ng/ml, as measured just outside of the blood outlet of said blood treating means - (2) Having a platelet factor 4 concn in range 500-10,000 ng/ ml, as measured just outside of the blood outlet of said blood treating means Wherein said blood treating means has a pressure drop index in the range 20-150, wherein said index is defined as a value obtained by a method in which heparin is added to bovine blood having a hematocrit value of 40% & total protein of 6.5 q/dl of plasma so that a final heparin concn becomes 5 units/ml of said bovine blood; the bovine blood is flowed through said blood treating means at flow rate of 50 ml/min, wherein, before the bovine blood enters said blood treating means, the same anticoagulant as used in a treat. of said patient with said extracorporeal blood circulation system is mixed into said bovine blood in the same manner as in said treat of the patient; a blood pressure difference (mmHg) as between the blood inlet & outlet of blood treat. means is measured 20 min. after the start of the flowing of said bovine blood; & said blood pressure difference is taken as a pressure drop index |
| PATENT PHOTOCOPY | Available on request |
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