PATENT ASSIGNEE'S COUNTRY | Canada |
UPDATE | 01.01 |
PATENT ASSIGNEE | Apoptogen Inc |
PATENT CLAIMS |
Method for identifying compd that modulates protein transla tion - Providing XIAP IRES reporter cistron, having > 60% identity to one of SEQ ID NOS:1,2, or 19-30 - Exposing said cistron to test compd - Determining the amount of translation from said XIAP IRES reporter cistron exposed to said compd., rel. to the amount of translation from said XIAP IRES reporter cistron not expo sed to said compd. Wherein a rel. increase in translation from said XIAP IRES reporter cistron exposed to said compd. indicates a compd that increases XIAP IRES-dependent protein translation, & wherein a rel. decrease in translation indicates that compd that decreases XIAP IRES-dependent protein translation |
PATENT PHOTOCOPY | Available on request |
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