Main > ENDOCRINOLOGY > Hormones. Protein > Thyroid Stimulating Hormones (TSH) > Mutagenesis

Product NE. A

PATENT ASSIGNEE'S COUNTRY Netherlands
UPDATE 11.99
PATENT ASSIGNEE Applied Research Systems ARS Holding NV
PATENT CLAIMS Modified hormone with N-linked oligosaccharide (I) chain completely eliminated from one but not both of the glycosylation sites on the alpha-subunit thereof, without removal of an (I) chain from the beta-subunit thereof, & exhibiting the same receptor binding capacity & plasma half-life as the natural hormone, but sufficiently low post-
receptor biol. activity to permit its use as competitive antagonist
PATENT PHOTOCOPY Available on request

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