Main > MEDICINE > Tissue > Sealant > Fibrin Sealant > Supplemented Fibrin Sealant

Product USA. A

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 09.00
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS Biocompatible supplemented tissue sealant compn
- At least one supplement selected from group: antibiotic
anesthetic, anticoagulant, CV drug, anti-inflammatory compd
cytotoxin or cell proliferation inhibitor, osteogenic compd.,
cartilage inducing compd., protease inhibitor, steroid
analgesic, antifungal, antiangiogenin, antifibrinolytic compd
antimicrobial, antiparasitic agent, antiseptic, antiviral compd
chemotherapeutic drug, lipid or liposome, oligonucleotide
or polynucleotide, an osteoconductive compd., polysaccha
ride, vasoconstrictor, vasodilator, vitamin, nutritional supple
ment & mineral
- Fibrinogen in amount which forms fibrin matrix; (a) wherein
said fibrinogen forms fibrin matrix when in presence of
thrombin & Ca(II) & water; (b) Further wherein said supple
ment is released from said fibrin matrix into the external
environment of use for sustained period; (c) Further wherein
the amount of supplement in compn is greater than amount
of supplement which is soluble in fibrin matrix & (d) wherein
said sustained period is greater than the period obtained
according to simple diffusion linetics
PATENT PHOTOCOPY Available on request

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