| PATENT ASSIGNEE'S COUNTRY | USA |
| UPDATE | 09.99 |
| PATENT ASSIGNEE | American Home Products |
| PATENT CLAIMS |
Method of inducing an increased MHC class I immune response in mammalian subject by HSV glycoprotein D (gD) antigen - Delivering to mammalian cell an effective amount of modi fied gene encoding HSV gD antigen lacking a functional native signal peptide, said modified gene under the con trol of regulatory seq. directing expression of said antigen in said cell - Wherein said amount is sufficient to permit the cell to accu mulate antigen in the cytoplasm, process the antigen for display on the surface of said cell, whereby said antigen interacts with MHC I molecules & induces primarily cellular immune response |
| PATENT PHOTOCOPY | Available on request |
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