| PATENT ASSIGNEE'S COUNTRY | USA |
| UPDATE | 08.00 |
| PATENT ASSIGNEE | This data is not available for free |
| PATENT CLAIMS |
Providing a transformed yeast cell comprising - A USP bimding partner being a member of nuclear recep tor family - USP or deriv thereof contg an apparent domain structure typical of the nuclear steroid receptor family, including an A/B (transactivation) domain, a C (DNA binding/dimeriza tion/transactivation) domain, a D (nuclear localization) do main, & an E (dimerization) domain capable of forming a functional USP-USP binding partner complex with said USP binding partner - Reporter gene, wherein expression of said reporter gene is transcriptionally activated by said functional USP-USP binding partner complex & whose expression in yeast is readily detectable in said transformed yeast cell & then - Incubating said transformed yeast cell in presence of test compd to form test culture, & in the absence of test compd to form control culture - Monitoringexpression of said reporter gene in test & control cultures |
| PATENT PHOTOCOPY | Available on request |
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