Main > PROTEINS > Proteomics > Virus Proteomics > Respiratory syncytial virus > Matrix protein > Interaction > Modulator. Screening

Product USA. A

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 01.00
PATENT ASSIGNEE American Cyanamid
PATENT CLAIMS Method of screening for modulators of RSV matrix protein interaction
- Culturing a host cell carrying a nucleic acid seq coding
(1) an RSV matrix protein
(2) Protein selected: MBP & glutathione-S-transferase
- Expressing said fused RSV matrix protein in cultured host
cell
- Measuring the interaction of said fused RSV matrix protein
- Adding a test sample to said expressed fused RSV ma
trix protein & measuring the effect on RSV matrix protein
interaction
Wherein an increase in the RSV matrix protein interaction indicates the test sample promotes RSV matrix protein interaction & decrease in RSV matrix protein interaction indicates test sample inhibits RSV matrix protein interaction
PATENT PHOTOCOPY Available on request

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