| TECHNOLOGY |
Liposome technology to target drugs to specific site in the body, reducing their toxicity. Liposomes are vesicles composed of one or more concentric phospholipid bilayers. In this technology, the liposomes are coated with PEG, are approximately 100 nm in diam.
The coating on the liposomes allows them to evade the immune system. Thus they can achieve a circulation half-life of several days. The liposomes can be adapted for a varie
ty of therapeutics by varying the number & compn of lipid layers, the size & charge of the liposome& the compn of the internal aq space. They can be used to deliver small molecules, proteins, peptides & oligonucleotides
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