Main > IMMUNOLOGY > Vaccines > Effectiveness Determn > Non-Human Animal Model > Chimeric Mouse

Product USA. A

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 04.00
PATENT ASSIGNEE Albert Einstein College of Medicine of Yeshiva University
PATENT CLAIMS A method of determining the effectiveness of a vaccine for inducing an active immune response in a mouse
- Providing a BNX mouse implanted with both human fetal
thymus tissue & human fetal liver tissue under the kidney
capsule of said mouse, said mouse being capable of
mounting murine cellular & humoral Ab responses, wherein
said mouse does not reject the implanted human tissue
- Injecting said mouse with said vaccine & determining if said
vaccine induces an active immune response in said mouse
PATENT PHOTOCOPY Available on request

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