Main > PHARMA. > Drug Side Effect > Screening Method. by > Gene Expression Assay

Product USA. A

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 03.00
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS Method of screening a drug for deleterious side effects on cell comprising
- Assaying for the amount of expression in the cell of > 2 ge
nes selected from: G6PD, Ca channel, Synaptogamin,
Neuromodulin, Calmodulin, Nicotinic acetylcholine recep
tor beta 2, VLDLR, Udulin1/Undulin/Extracellular matrix
glycoprotein, Pyruvate dehydrogenase E1, Apolipoprotein
B100, Hepatocyte gf, IGF binding protein 1, Ubiquitin, Bone
morphogenetic protein precursor, Cytochrome p450-2E1,
& Thymosin beta-10
Wherein expression in the cell is assayed before & after the cell has been contacted with the drug
Wherein alteration of the amount of expression of at least one of these genes by the drug is indicative of deleterious side effect
PATENT PHOTOCOPY Available on request

Want more information ?
Interested in the hidden information ?
Click here and do your request.


back