PATENT ASSIGNEE'S COUNTRY | USA |
UPDATE | 04.00 |
PATENT ASSIGNEE | This data is not available for free |
PATENT CLAIMS |
Method for detecting target HGBV nucleic acid in test sample - Reacting test sample with HGBV polynucleotide probe comprising seq of > 15 contiguous nucleotides, wherein said seq selectively hybridizes to genome of HGBV or its full complement, wherein said HGBV comprises a positive stranded RNA viral genome comprising an ORF encoding a polyprotein, wherein said polyprotein (i) has AA seq having > 35% identity to polyprotein seq selected from: SEQ ID NO:387, 394 & 401 wherein said % identity is determined by using the computer program GAP of the Wisconsin Pa ckage, Version 8 with the gap penalty set to 3 & gap exten sion penalty set to 0.1 & (ii) is not immunoreactive with an Ab that specifically reacts with protein encoded by virus selec ted from group: hepatitis A, B, C, Delta, & E virus, under con ditions & for time which allows the formation of a complex between probe & target HGBV nucleic acid in test sample - Detecting the complex that contains the target HGBV nu clic acid wherein the presence of complex is indicative of presence of target HGBV |
PATENT PHOTOCOPY | Available on request |
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