| PATENT ASSIGNEE'S COUNTRY | USA |
| UPDATE | 08.00 |
| PATENT ASSIGNEE | ZymoGenetics |
| PATENT CLAIMS |
Method of determn protein prohormone substrates of a human prohormone convertase 4 protein comprising cultu ring a cell into which has been introduced an expression vector comprising the following operably linked elements - Transcription promoter - DNA segment encoding a prohormone convertase protein having a AA seq as shown in SEQ ID NO:2 from AA No. 20 (Arg) to AA No. 755 (Thr) & - Transcription terminator Wherein the cell expresses a human prohormone convertase protein encoded by the DNA segment & co-ex presses a test substrate prohormone protein Detecting cleavage prodts resulting from cleavage of test substrate by human prohormone convertase 4 protein - |
| PATENT PHOTOCOPY | Available on request |
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